Coumarins of plants in vivo and cell cultures in vitro

Khandy M., Grigorchuk V., Gorpenchenko T.

В издании "Phytopharm 2023", XXIV International Congress: Proceeding of the congress

Год: 2023 Страницы: 45

Coumarins are a large group of secondary metabolites that have antispasmodic, sedative, diuretic, anthelmintic, analgesic, antimicrobial, antitumor and other properties. Rare groups of coumarins include furanocoumarins and pyranocoumarins, which, depending on the position of the third ring (furan or pyran, respectively), are angular and linear form. Depending on the modification of the structure, there is a change or expansion of biologically active properties. Phlojodicarpus sibiricus, an endemic of the Far East, was previously included in the State Register of Medicines of the Russian Federation as a source of pyranocoumarins. Now P. sibiricus is an endangered plant. The related species P. villosus may be a source of pyranocoumarins. However, its qualitative composition of secondary metabolites has been little studied.

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