Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy
Chuang W.H., Pislyagin E., Lin L.Y., Menchinskaya E., Chernikov O., Kozhemyako V., Gorpenchenko T., Manzhulo I., Chaikina E., Agafonova I., Silchenko A., Avilov S., Stonik V., Tzou Sh.C., Aminin D., Wang Y.M.
В журналеCancer Cell International
Год: 2023 Том: 23 ArticleID: 292
Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeutic option against solid tumors.