Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy

Chuang W.H., Pislyagin E., Lin L.Y., Menchinskaya E., Chernikov O., Kozhemyako V., Gorpenchenko T., Manzhulo I., Chaikina E., Agafonova I., Silchenko A., Avilov S., Stonik V., Tzou Sh.C., Aminin D., Wang Y.M.

В журнале Cancer Cell International

Год: 2023 Том: 23 ArticleID: 292

Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeutic option against solid tumors.

DOI 10.1186/s12935-023-03141-z

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