Heterohromatin and microevolution

Kartavtseva I. V.

В издании Modern achievements in population, evolutionary and ecological genetics (MAPEEG - 2011): Program and Abstract of International Symposium

Год: 2011 Страницы: 18

The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes. C-banding techniques and restriction enzyme digestion have demonstrated that there are different kinds of heterochromatin, with a great variability, among many species. The pericentric heterochromatin had the highest coverage of retroelements and tandem repeats, while intercalary heterochromatin was enriched with segmental duplications.DNA transposable elements, minisatellites, and satellites than does the compact intercalary heterochromatin. As known, the most ancestral karyotype, shows the greatest amount of constitutive heterochromatin in all of the reported karyotypes. The chromosomal evolution of wood mice Sylvaemus and Apodemus (2n=46, 48) is characterized by changes in quantity of centromeric and telomeric heterochromatin (Kartavtseva 2002). Variability of pericentric heterochromatin in wood mice species discussed.