Galina Tchernoded

Laboratory of Bioengineering
Leading Engineer

Selected publications


2025 - Update on the role of different lighting parameters in the regulation of secondary metabolism in Lithospermum erythrorhizon Sieb. et Zucc. calli Veremeichik G.N., Silantieva S.A., Grigorchuk V.P., Tikhonova O.A., Brodovskaya E.V., Subbotin E.P., Tchernoded G.K., Fedoreyev S.A., Mishchenko N.P., Vasileva E.A., Khopta A.A., Kozhanov S.O., Sibirev A.S., Kulchin Y.N., Bulgakov V.P. Plant Cell, Tissue and Organ Culture Year: 2025 Volume: 163 Article ID: 74 DOI: 10.1007/s11240-025-03280-3
2025 - Calcium-dependent regulation of anthraquinone biosynthesis by the sweet potato Ib-rolb/C gene in Rubia cordifolia callus cultures Shkryl Yu., Grishchenko O., Vasileva E., Mishchenko N., Vasyutkina E., Alaverdov E., Kudinova O., Tchernoded G., Fialko A., Tsydeneshieva Zh., Sorokina M., Yaroshenko Yu., Degtyarenko A., Fedoreyev S., Bulgakov V., Yugay Yu. Phytochemistry Year: 2025 Volume: 242 Article ID: 114710 DOI: 10.1016/j.phytochem.2025.114710
2025 - Diferential regulation of cafeoylquinic acid production in Cynara cardunculus var. altilis DC calli by modulating qualitative and quantitative LED‑lighting parameters Veremeichik G.N., Silantieva S.A., Grigorchuk V.P., Tikhonova O.A., Brodovskaya E.V., Subbotin E.P., Tchernoded G.K., Yaroshenko Y.I., Kozhanov S.O., Sibirev A.V., Kulchin Y.N., Bulgakov V.P. Plant Biotechnology Reports Year: 2025 Volume: 19 Pages: 815-825 DOI: 10.1007/s11816-025-01005-8
2024 - Artificial monochromatic red and green light induces the biosynthesis of rosmarinic acid in long-term cultured calli of Mertensia maritima (L.) Veremeichik G.N., Silantieva S.A., Grigorchuk V.P., Brodovskaya E.V., Subbotin E.P., Tchernoded G.K., Tikhonova O.A., Bulgakov V.P., Kulchin Y.N. Plant Cell, Tissue and Organ Culture Year: 2024 Volume: 159 Article ID: 67 DOI: 10.1007/s11240-024-02926-y
2024 - Exosome-like Nanoparticles, High in Trans-δ-Viniferin Derivatives, Produced from Grape Cell Cultures: Preparation, Characterization, and Anticancer Properties Shkryl Yu., Tsydeneshieva Zh., Menchinskaya E., Rusapetova T., Grishchenko O., Mironova A., Bulgakov D., Gorpenchenko T., Kazarin V., Tchernoded G., Bulgakov V., Aminin D., Yugay Yu. Biomedicines Year: 2024 Volume: 12 Issue: 9 Article ID: 2142 DOI: 10.3390/biomedicines12092142
2023 - Accumulation of Polyphenols and Naphthoquinones in Morphogenic Cultures of Two Drosera Species Morshneva A.V., Khandy M.T., Grigorchuk V.P., Chernoded G.K., Gorpenchenko T.Yu. Russian Journal of Plant Physiology Year: 2023 Volume: 70 Pages: 175 DOI: 10.1134/S1021443723603075
2023 - HPLC-MS Analysis of Ginsenosides in Morphogenic Cell Cultures of Ginseng (Panax ginseng C.A. Meyer) Gorpenchenko T.Yu., Grigorchuk V.P., Makhankov V.V., Kochkin D.V., Vologzhanina Yu.V., Khandy M.T., Chernoded G.K., Zhuravlev Yu.N. Russian Journal of Plant Physiology Year: 2023 Volume: 70 Article ID: 172 DOI: 10.1134/S1021443723603087
2023 - Isolation and Characterization of Extracellular Vesicles from Arabidopsis thaliana Cell Culture and Investigation of the Specificities of Their Biogenesis Yugay Y., Tsydeneshieva Z., Rusapetova T., Grischenko O., Mironova A., Bulgakov D., Silant’ev V., Tchernoded G., Bulgakov V., Shkryl Y. Plants (Basel) Year: 2023 Volume: 12 Number: 20 Article ID: 3604 DOI: 10.3390/plants12203604
2023 - Auxin-dependent regulation of growth via rolB-induced modulation of the ROS metabolism in the long-term cultivated pRiA4-transformed Rubia cordifolia L. calli Veremeichik G.N., Gorpenchenko T.Y., Rusapetova T.V., Brodovskaya E.V., Tchernoded G.K., Bulgakov D.V., Shkryl Y.N., Bulgakov V.P. Plant Physiology and Biochemistry Year: 2023 Volume: 202 Article ID: 107932 DOI: 10.1016/j.plaphy.2023.107932
2023 - Enhanced Production of Nitrogenated Metabolites with Anticancer Potential in Aristolochia manshuriensis Hairy Root Cultures Shkryl Y.N., Tchernoded G.K., Yugay Y.A., Grigorchuk V.P., Sorokina M.R., Gorpenchenko T.Y., Kudinova O.D., Degtyarenko A.I., Onishchenko M.S., Shved N.A., Kumeiko V.V., Bulgakov V.P. International Journal of Molecular Sciences Year: 2023 Volume: 24 Number: 14 Article ID: 11240 DOI: 10.3390/ijms241411240
2022 - Callus Culture of Scorzonera radiata as a New, Highly Productive and Stable Source of Caffeoylquinic Acids. Grishchenko O.V., Grigorchuk V.P., Tchernoded G.K., Koren O.G., Bulgakov V.P. Molecules Year: 2022 Volume: 27 Number: 7989 DOI: 10.3390/molecules27227989
2022 - Histological Structure and Composition of Secondary Metabolites in Cell Culture of Drosera rotundifolia L. Khandy M.T., Chernoded G.K., Grigorchuk V.P., Vereshchagina Yu.V., Morshneva A.V., Gorpenchenko T.Yu. Russian Journal of Plant Physiology Year: 2022 Volume: 69 Number: 5 Pages: 451-461 DOI: 10.1134/S1021443722050090
2022 - Transcriptional regulation of enzymes involved in ROS metabolism and abiotic stress resistance in rolC-transformed cell cultures Shkryl Yu., Veremeichik G., Avramenko T., Gorpenchenko T., Tchernoded G., Bulgakov V. Plant Growth Regulation Year: 2022 Volume: 97 Number: 3 Pages: 485-497 DOI: 10.1007/s10725-022-00812-1
2021 - Inhibition of the JAZ1 gene causes activation of camalexin biosynthesis in Arabidopsis callus cultures Makhazen D.S., Veremeichik G.N., Shkryl Y.N., Tchernoded G.K., Grigorchuk V.P., Bulgakov V.P. Journal of Biotechnology Year: 2021 Volume: 342 Pages: 102-113 DOI: 10.1016/j.jbiotec.2021.10.012
2021 - RNA inhibition of the JAZ9 gene increases the production of resveratrol in grape cell cultures Makhazen D.S., Veremeichik G.N., Shkryl Y.N., Grigorchuk V.P., Tchernoded G.K., Degtyarenko A.I., Bulgakov V.P. Plant Cell, Tissue and Organ Culture Year: 2021 Volume: 147 Pages: 611–618 DOI: 10.1007/s11240-021-02152-w
2019 - INTERACTION OF YERSINIA PSEUDOTUBERCULOSIS WITH CALLUSES PANAX GINSENG C.A. MEY Timchenko N.F., Eliseykina M.G., Chernoded G.K., Grishchenko O.G., Bulgakov V.P. Health. Medical ecology. Science Year: 2019 Volume: 79 Number: 3 Pages: 4-7 DOI: 10.5281/zenodo.3559604 IN RUSSIAN
2019 - Activation of anthraquinone biosynthesis in long-cultured callus culture of Rubia cordifolia transformed with the rolA plant oncogene Veremeichik G.N., Bulgakov V.P., Shkryl Y.N., Silantieva S.A., Makhazen D.S., Tchernoded G.K., Mischenko N.P., Fedoreyev S.A., Vasileva E.A. Journal of Biotechnology Year: 2019 Volume: 306 Pages: 38-46 DOI: 10.1016/j.jbiotec.2019.09.007
2019 - Tempo-spatial pattern of stepharine accumulation in Stephania glabra morphogenic tissues Gorpenchenko T.Y.; Grigorchuk V.P.; Bulgakov D.V.; Tchernoded G.K.; Bulgakov V.P. International Journal of Molecular Sciences Year: 2019 Volume: 20 Number: 4 Article ID: 808 DOI: 10.3390/ijms20040808
2017 - Stepharine production in morphogenic cell cultures of Stephania glabra (ROXB.) Miers Gorpenchenko T.Y., Grigorchuk V.P., Fedoreyev S.A., Tarbeeva D.V., Tchernoded G.K., Bulgakov V.P. Plant Cell, Tissue and Organ Culture Year: 2017 Volume: 128 Number: 1 Pages: 67-76 DOI: 10.1007/s11240-016-1083-5
2016 - RolB gene-induced production of isoflavonoids in transformed Maackia amurensis cells Grishchenko O.V., Kiselev K.V., Tchernoded G.K., Fedoreyev S.A., Veselova M.V., Bulgakov V.P., Zhuravlev Y.N. Applied Microbiology and Biotechnology Year: 2016 Number: 100 Issue: 17 Pages: 7479-7489 DOI: 10.1007/s00253-016-7483-y
2014 - The rolC gene increases caffeoylquinic acid production in transformed artichoke cells. Vereshchagina Y.V., Bulgakov V.P., Grigorchuk V.P., Rybin V.G., Veremeichik G.N., Tchernoded G.K., Gorpenchenko T.Y., Koren O.G., Phan N.H., Minh N.T., Chau L.T., Zhuravlev Y.N. Applied Microbiology and Biotechnology Year: 2014 Volume: 98 Number: 18 Pages: 7773-7780 DOI: 10.1007/s00253-014-5869-2
2013 - The influence of the rolC gene on isoflavonoid production in callus cultures of Maackia amurensis Grishchenko O.V., Kiselev K.V., Tchernoded G.K., Fedoreyev S.A., Veselova M.V., Bulgakov V.P., Zhuravlev Y.N. Plant Cell, Tissue and Organ Culture Year: 2013 Volume: 113 Number: 3 Pages: 429-435 DOI: 10.1007/s11240-012-0283-x
2012 - Can plant oncogenes inhibit programmed cell death? The rolB oncogene reduces apoptosis-like symptoms in transformed plant cells. Gorpenchenko T.Y., Aminin D.L., Vereshchagina Y.V., Shkryl Y.N., Veremeichik G.N., Tchernoded G.K., Bulgakov V.P. Plant Signaling & Behavior Year: 2012 Volume: 7 Number: 9 Pages: 1058-1061 DOI: 10.4161/psb.21123
2012 - Production of allantoin, rabdosiin and rosmarinic acid in callus cultures of the seacoastal plant Mertensia maritima (Boraginaceae) Fedoreyev S.A., Inyushkina Y.V., Bulgakov V.P., Veselova M.V., Tchernoded G.K., Gerasimenko A.V., Zhuravlev Y.N. Plant Cell, Tissue and Organ Culture Year: 2012 Volume: 110 Number: 1 Pages: 183-188 DOI: 10.1007/s11240-012-0125-x
2012 - The rolB gene suppresses reactive oxygen species in transformed plant cells through sustained activation of antioxidant defense Bulgakov V.P., Gorpenchenko T.Y., Veremeichik G.N., Shkryl Y.N., Tchernoded G.K., Bulgakov D.V., Aminin D.L., Zhuravlev Y.N. Plant Physiology Year: 2012 Volume: 158 Number: 3 Pages: 1371–1381 DOI: 10.1104/pp.111.191494
2011 - Programmed cell death in Rubia cordifolia cells transformed by agrobacterial rolB oncogene. Gorpenchenko T.Y., Tchernoded G.K., Bulgakov V.P. Modern achievements in population, evolutionary and ecological genetics (MAPEEG - 2011): Program and Abstract of International Symposium Year: 2011 Pages: 17
2011 - Catechin production in cultured cells of Taxus cuspidata and Taxus baccata Bulgakov V.P., Tchernoded G.K., Veselova M.V., Fedoreyev S.A., Muzarok T.I., Zhuravlev Y.N. Biotechnology Letters Year: 2011 Volume: 33 Pages: 1879–1883 DOI: 10.1007/s10529-011-0632-6
2011 - Mutation of Panax ginseng genes during long-term cultivation of ginseng cell cultures Kiselev K.V., Shumakova O.A., Tchernoded G.K. Journal of Plant Physiology Year: 2011 Volume: 168 Number: 11 Pages: 1280-1285 DOI: 10.1016/j.jplph.2011.01.028
2009 - Nucleotide substitutions in rolC and nptII gene sequences during long-term cultivation of Panax ginseng cell cultures Kiselev K.V., Turlenko A.V., Tchernoded G.K., Zhuravlev Y.N. Plant Cell Reports Year: 2009 Volume: 28 Number: 8 Pages: 1273-1278 DOI: 10.1007/s00299-009-0728-9
2009 - Somatic embryogenesis in the Panax ginseng cell culture induced by the rolC oncogene is associated with increased expression of WUS and SERK genes Kiselev K.V., Tchernoded G.K. Russian Journal of Genetics Year: 2009 Volume: 45 Number: 4 Pages: 445-452 DOI: 10.1134/S1022795409040097
2008 - Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim. Fedoreyev S.A., Bulgakov V.P., Grishchenko O.V., Veselova M.V., Krivoschekova O.E., Kulesh N.I., Denisenko V.A., Tchernoded G.K., Zhuravlev Y.N. Journal of Agricultural and Food Chemistry Year: 2008 Volume: 56 Number: 16 Pages: 7023-7031 DOI: 10.1021/jf801227q
2008 - Defense response mechanisms of ginseng callus cultures induced by Yersinia pseudotuberculosis, a human pathogen Persiyanova E.V., Kiselev K.V., Bulgakov V.P., Timchenko N.F., Chernoded G.K., Zhuravlev Yu.N. Russian Journal of Plant Physiology Year: 2008 Volume: 55 Number: 6 Pages: 748-755 DOI: 10.1134/S1021443708060034
2008 - Individual and Combined Effects of the rolA, B and C Genes on Anthraquinone Production in Rubia cordifolia Transformed Calli Shkryl Y.N., Veremeichik G.N., Bulgakov V.P., Tchernoded G.K., Mischenko N.P., Fedoreyev S.A., Zhuravlev Y.N. Biotechnology and Bioengineering Year: 2008 Volume: 100 Number: 1 Pages: 118-125 DOI: 10.1002/bit.21727
2008 - Calcium-dependent mechanism of somatic embryogenesis in Panax ginseng cell cultures expressing the rolC oncogene Kiselev K.V., Gorpenchenko T.Y., Tchernoded G.K., Dubrovina A.S., Grishchenko O.V., Bulgakov V.P., Zhuravlev Y.N. Molecular Biology Year: 2008 Volume: 42 Number: 2 Pages: 243-252 DOI: 10.1134/S0026893308020106
2007 - Chemical composition and pharmacological activity of anthraquinones from Rubia cordifolia cell culture Mishchenko N.P., Fedoreev S.A., Bryukhanov V.M., Zverev Ya.F., Lampatov V.V., Azarova O.V., Shkryl' Yu.N., Chernoded G.K. Pharmaceutical Chemistry Journal Year: 2007 Volume: 41 Number: 11 Pages: 605-609 DOI: 10.1007/s11094-008-0021-1
2007 - High Rabdosiin and Rosmarinic Acid Production in Eritrichium sericeum Callus Cultures and the Effect of the Calli on Masugi-Nephritis in Rats Inyushkina Y.V., Bulgakov V.P., Veselova M.V., Bryukhanov V.M., Zverev Y.F., Lampatov V.V., Azarova O.V., Tchernoded G.K., Fedoreyev S.A., Zhuravlev Y.N. Bioscience, Biotechnology and Biochemistry Year: 2007 Volume: 71 Number: 5 Pages: 1286-1293 DOI: 10.1271/bbb.60684
2006 - The Agrobacterium rhizogenes rolC-gene-induced somatic embryogenesis and shoot organogenesis in Panax ginseng transformed calluses Gorpenchenko T.Y., Kiselev K.V., Bulgakov V.P., Tchernoded G.K., Bragina E.A., Khodakovskaya M.V., Koren O.G., Batygina T.B., Zhuravlev Y.N. Planta Year: 2006 Volume: 223 Number: 3 Pages: 457-467 DOI: 10.1007/s00425-005-0102-2
2005 - Somatic embryogenesis in transformed cell culture of Panax ginseng Gorpenchenko T.Y., Kiselev K.V., Bulgakov V.P., Tchernoded G.K., Bragina E.A., Khodakovskaya M.V., Koren O.G., Batygina T.B., Zhuravlev Yu.N. XVII International Botanical Congress: Abstract book Year: 2005 Pages: 648
2005 - Caffeic Acid Metabolites from Eritrichium sericeum Cell Cultures Fedoreyev S.A., Veselova M.V., Krivoschekova O.E., Mischenko N.P., Denisenko V.A., Dmitrenok P.S., Glazunov V.P., Bulgakov V.P., Tchernoded G.K., Zhuravlev Y.N. Planta Medica Year: 2005 Volume: 71 Number: 5 Pages: 446-451 DOI: 10.1055/s-2005-864141
2005 - Inhibitory effect of the Agrobacterium rhizogenes rolC gene on rabdosiin and rosmarinic acid production in Eritrichium sericeum and Lithospermum erythrorhizon transformed cell cultures Bulgakov V.P., Veselova M.V., Tchernoded G.K., Kiselev K.V., Fedoreyev S.A., Zhuravlev Y.N. Planta Year: 2005 Volume: 221 Number: 4 Pages: 471-478 DOI: 10.1007/s00425-004-1457-5
2004 - The rolB and rolC genes activate synthesis of anthraquinones in Rubia cordifolia cells by mechanism independent of octadecanoid signaling pathway Bulgakov V.P., Tchernoded G.K., Mischenko N.P., Shkryl Y.N., Fedoreyev S.A., Zhuravlev Y.N. Plant Science Year: 2004 Volume: 166 Number: 4 Pages: 1069-1075 DOI: 10.1016/j.plantsci.2003.12.027
2003 - Increase in anthraquinone content in Rubia cordifolia cells transformed by rol genes does not involve activation of the NADPH oxidase signaling pathway Bulgakov V.P., Tchernoded G.K., Mischenko N.P., Shkryl Y.N., Glazunov V.P., Fedoreyev S.A., Zhuravlev Y.N. Biochemistry (Moscow) Year: 2003 Volume: 68 Number: 7 Pages: 795-801 DOI: 10.1023/A:1025091118544
2003 - Effects of Ca2+, channel blockers and protein kinase/phosphatase inhibitors on growth and anthraquinone production in Rubia cordifolia callus cultures transformed by the rolB and rolC genes Bulgakov V.P., Tchernoded G.K., Mischenko N.P., Shkryl Y.N., Glazunov V.P., Fedoreyev S.A., Zhuravlev Y.N. Planta Year: 2003 Volume: 217 Number: 3 Pages: 349-355 DOI: 10.1007/s00425-003-0996-5
2002 - Carbohydrase activities of the rolC-gene transformed and non-transformed ginseng cultures Bulgakov V.P., Kusaykin M., Tchernoded G.K., Zvyagintseva T.N., Zhuravlev Y.N. Fitoterapia Year: 2002 Volume: 73 Number: 7-8 Pages: 638-643 DOI: 10.1016/S0367-326X(02)00231-9
2002 - Effect of salicylic acid, methyl jasmonate, ethephon and cantharidin on anthraquinone production by Rubia cordifolia callus cultures transformed with the rolB and rolC gene Bulgakov V.P., Tchernoded G.K., Mischenko N.P., Khodakovskaya M., Glazunov V.P., Radchenko S.V., Zvereva E.V., Fedoreyev S.A., Zhuravlev Y.N. Journal of Biotechnology Year: 2002 Volume: 97 Number: 3 Pages: 213-221 DOI: 10.1016/S0168-1656(02)00067-6
2000 - Chromosome variation in ginseng cells transformed with the rolC plant oncogene Bulgakov V.P., Lauve L.S., Tchernoded G.K., Khodakovskaya M.V., Zhuravlev Y.N. Russian Journal of Genetics Year: 2000 Volume: 36 Number: 2 Pages: 150-156
1999 - Anthraquinone production by callus cultures of Rubia cordifolia Mischenko N.P., Fedoreyev S.A., Glazunov V.P., Chernoded G.K., Bulgakov V.P., Zhuravlev Y.N. Fitoterapia Year: 1999 Volume: 70 Number: 6 Pages: 552-557 DOI: 10.1016/S0367-326X(99)00085-4
1998 - The impact of plant rolC oncogene on ginsenoside production by ginseng hairy root cultures Bulgakov V.P., Khodakovskaya M.V., Labetskaya N.V., Chernoded G.K., Zhuravlev Y.N. Phytochemistry Year: 1998 Volume: 49 Number: 7 Pages: 1929-1934 DOI: 10.1016/S0031-9422(98)00351-3
1996 - Source-sink relations in Far-Estern rice cultivars as related to their productivity Kholupenko I.P., Burundukova O.L., Zhemchugova V.P., Voronkova N.M., Tchernoded G.K. Russian Journal of Plant Physiology Year: 1996 Volume: 43 Number: 2 Pages: 165-173