Koldaev V.M., Kropotov A.V.
Pacific medical journal 2021; (3): 24-28
The survey of the publications on cytoprotective antidiabetic, antimicrobial, antitumor and neuroprotective effects of the heterocyclic plant anthocyan glycosides, and also on their use to adjust metabolic processes in case of obesity. Having analyzed of publications it was concluded that wide spectrum of preventive and therapeutic effects of these glycosides mainly depends on their high antioxidant activity. It provides inactivation of the free radicals and also the ability to modulate intracellular energy systems of the mitochondria. Elimination of the manifestation and consequences of the oxidative stress using anthocyans is a forward-looking strategy to normalize metabolic disorders in case of cardiovascular pathology. High lability of anthocyans limits their usage in food and medical products. It is considered to be a complex and unsolved problem. The research in this field should primarily be aimed at increasing anthocyans' resistance and preventing their degradation during processing and storage of the plant material.