Mixotrophy, a more promising culture mode: Multi-faceted elaboration of carbon and energy metabolism mechanisms to optimize microalgae culture

Shan S., Manyakhin A.Yu., Wang C., Ge B., Han J., Zhang X., Zhou Ch., Yan X., Ruan R., Cheng P.

В журнале Bioresource Technology

Год: 2023 Том: 386 ArticleID: 129512

Some mixotrophic microalgae appear to exceed the sum of photoautotrophy and heterotrophy in terms of biomass production. This paper mainly reviews the carbon and energy metabolism of microalgae to reveal the synergistic mechanisms of the mixotrophic mode from multiple aspects. It explains the shortcomings of photo autotrophic and heterotrophic growth, highlighting that the mixotrophic mode is not simply the sum of pho toautotrophy and heterotrophy. Specifically, microalgae in mixotrophic mode can be divided into separate parts of photoautotrophic and heterotrophic cultures, and the synergistic parts of photoautotrophic culture enhance aerobic respiration and heterotrophic culture enhance the Calvin cycle. Additionally, this review argues that current deficiencies in mixotrophic culture can be improved by uncovering the synergistic mechanism of the mixotrophic mode, aiming to increase biomass growth and improve quality. This approach will enable the full utilization of advantages in various fields, and provide research directions for future microalgal culture.

DOI 10.1016/j.biortech.2023.129512